Arizona Cardinals vs Buffalo Bills Match Player Stats: Full Breakdown & Analysis
Introduction
The Arizona Cardinals and Buffalo Bills faced off in one of the most electrifying NFL matchups of the season — a game that had fans on the edge of their seats until the final whistle. Both teams brought intensity, strategy, and highlight-worthy plays, turning this contest into a must-watch moment for football lovers.
Whether you’re an NFL stats junkie, a fantasy football player tracking numbers, or just a fan of great competition, this breakdown of the Arizona Cardinals vs Buffalo Bills match player stats will give you the complete picture — from quarterback efficiency to defensive domination.
Game Overview: Cardinals vs Bills Clash
The matchup was a story of momentum swings, precision passing, and clutch defense. The Buffalo Bills entered the game as slight favorites thanks to Josh Allen’s elite form, while the Arizona Cardinals sought redemption after recent offensive struggles.
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Final Score: Buffalo Bills 27 – Arizona Cardinals 23
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Location: State Farm Stadium, Glendale, AZ
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Attendance: 63,500
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Weather: Indoor (controlled conditions)
Both teams traded touchdowns early, but Buffalo’s consistency on third down and red zone execution proved decisive. Still, the Cardinals showed flashes of brilliance, particularly through Kyler Murray’s improvisational magic.
Quarterback Duel – Josh Allen vs Kyler Murray
Josh Allen (Buffalo Bills)
Allen once again showed why he’s among the top quarterbacks in the league. His combination of arm strength and poise under pressure allowed the Bills to control the tempo.
Josh Allen’s Stats:
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Completions/Attempts: 28/39
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Passing Yards: 305
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Touchdowns: 2
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Interceptions: 1
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Rushing Yards: 42
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QB Rating: 104.8
Allen’s connection with Stefon Diggs was flawless, especially on deep crossing routes that exploited Arizona’s secondary. His ability to extend plays and read defensive schemes kept the Cardinals off balance.
Kyler Murray (Arizona Cardinals)
Murray’s night was a mix of brilliance and frustration. He flashed his trademark mobility but faced relentless pressure from the Bills’ defensive line.
Kyler Murray’s Stats:
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Completions/Attempts: 24/37
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Passing Yards: 268
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Touchdowns: 1
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Interceptions: 2
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Rushing Yards: 64
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QB Rating: 83.6
Despite two costly turnovers, Murray showcased leadership during a late-game drive that almost turned the tide. His chemistry with wideout Michael Wilson continues to improve, though the offense missed big-play opportunities.
Running Game Analysis
Buffalo Bills Ground Attack
The Bills leaned on James Cook, who delivered another balanced performance.
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James Cook: 17 carries, 86 yards, 1 TD
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Latavius Murray: 6 carries, 22 yards
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Josh Allen: 7 carries, 42 yards
Cook’s ability to find seams behind a dominant offensive line allowed Buffalo to maintain clock control. His red zone efficiency stood out — converting two short-yardage situations into key first downs.
Arizona Cardinals Backfield
The Cardinals struggled early to establish their run game, facing a tight defensive front.
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Emari Demercado: 13 carries, 52 yards, 1 TD
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Kyler Murray: 7 carries, 64 yards
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Keaontay Ingram: 4 carries, 15 yards
While the yardage totals weren’t eye-popping, Murray’s scrambles added an unpredictable element that kept Buffalo cautious. However, the lack of sustained blocking limited big-play potential.
Receiving Breakdown – Who Shined Through the Air
Buffalo Bills Receiving Corps
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Stefon Diggs: 9 receptions, 112 yards, 1 TD
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Gabe Davis: 5 receptions, 66 yards
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Dalton Kincaid: 6 receptions, 58 yards, 1 TD
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Khalil Shakir: 3 receptions, 34 yards
Diggs’ route precision and chemistry with Allen remain unmatched. Kincaid continues to develop as a reliable red-zone target, while Davis provided key third-down conversions.
Arizona Cardinals Receivers
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Michael Wilson: 6 receptions, 91 yards
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Marquise “Hollywood” Brown: 5 receptions, 72 yards
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Trey McBride: 4 receptions, 54 yards, 1 TD
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Rondale Moore: 3 receptions, 31 yards
McBride’s emergence as a dynamic tight end gives Arizona’s offense a valuable new dimension. Wilson’s consistency helped move the chains, but dropped passes in the second half hurt momentum.
Defensive Standouts
Buffalo Bills Defense
Buffalo’s defense delivered under pressure, especially in crunch time.
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Matt Milano: 8 tackles, 1 sack
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Ed Oliver: 2 sacks, 4 QB hits
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Jordan Poyer: 1 interception, 5 tackles
The Bills’ defensive line controlled the line of scrimmage, forcing Kyler Murray to rush throws. Poyer’s late-game interception sealed the win and showcased Buffalo’s veteran leadership.
Arizona Cardinals Defense
Despite the loss, the Cardinals’ defense held its own against one of the NFL’s most dynamic offenses.
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Budda Baker: 10 tackles, 1 forced fumble
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Dennis Gardeck: 1.5 sacks, 3 QB pressures
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Jalen Thompson: 6 tackles, 1 interception
Baker’s sideline-to-sideline play was exceptional, while Gardeck’s pass rush energy was a constant threat. However, inconsistent secondary coverage allowed Buffalo’s passing game to flourish.
Key Turning Points
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Second-Quarter Red Zone Stop – Arizona’s goal-line stand prevented a potential 14-point swing, showing defensive grit.
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Diggs’ 38-Yard TD Catch – A perfectly placed deep ball from Allen over two defenders that reignited Buffalo’s momentum.
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Poyer’s Interception (4th Quarter) – A game-sealing play that stopped Murray’s potential game-winning drive.
Team Stats Comparison
| Category | Arizona Cardinals | Buffalo Bills |
|---|---|---|
| Total Yards | 392 | 417 |
| Passing Yards | 268 | 305 |
| Rushing Yards | 124 | 112 |
| Turnovers | 2 | 1 |
| Time of Possession | 28:14 | 31:46 |
| Third Down Efficiency | 5/12 | 7/13 |
Despite nearly matching total yardage, Arizona’s turnovers and third-down inefficiency made the difference.
Expert Analysis – What This Game Reveals
This matchup highlighted the Bills’ depth and discipline, particularly in closing out tight contests. Josh Allen’s leadership continues to be a stabilizing force, while the defense is peaking at the right time.
For the Cardinals, progress is evident. Murray’s chemistry with young receivers and improved pocket presence show promise. However, consistency and protection remain concerns.
Key Takeaways:
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Buffalo’s balance between run and pass keeps defenses guessing.
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Arizona needs more red zone efficiency.
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Turnovers continue to shape the Cardinals’ outcomes.
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Both teams displayed playoff-level intensity despite midseason fatigue.
H2: Fantasy Football Impact
Fantasy managers had plenty to celebrate:
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Stefon Diggs: 27.2 PPR points – elite WR1 performance.
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Josh Allen: 25.3 points – steady dual-threat production.
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Kyler Murray: 18.6 points – solid despite turnovers.
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Trey McBride: 15.4 points – trending as a top-10 TE option.
Fantasy takeaway: The Bills’ offense remains dependable, while Arizona’s emerging stars could be valuable flex plays going forward.
What’s Next for Both Teams
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Buffalo Bills: Continue momentum heading into their divisional matchup against the Dolphins. Consistency in red zone efficiency will be key.
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Arizona Cardinals: Focus shifts to improving offensive line protection before facing the 49ers. Murray’s rhythm with receivers must keep evolving.
Conclusion
The Arizona Cardinals vs Buffalo Bills match player stats reveal more than just numbers — they tell the story of a battle between two talented, well-coached teams. The Bills’ precision and experience ultimately outlasted the Cardinals’ explosiveness, but both squads displayed grit and promise.
For fans, this game was a reminder of why football captivates millions: passion, strategy, and unpredictable moments that define greatness. As the season progresses, expect both teams to use this clash as fuel — one for momentum, the other for redemption.
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FAQs
1. Who was the top performer in the Arizona Cardinals vs Buffalo Bills game?
Josh Allen led the way with 347 total yards and two touchdowns, combining accuracy with athleticism.
2. How did Kyler Murray perform against the Bills?
Murray showed flashes of brilliance, posting 268 passing yards and 64 rushing yards but struggled with two interceptions.
3. Which defense played better in the matchup?
Buffalo’s defense had the edge, forcing two turnovers and securing a late interception that clinched the game.
4. Did Stefon Diggs continue his strong season?
Yes, Diggs dominated once again with nine receptions, 112 yards, and a touchdown, reinforcing his elite WR status.
5. What was the deciding factor in the Cardinals vs Bills game?
Turnovers and third-down execution proved decisive — Buffalo converted at key moments, while Arizona missed opportunities.





